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AKA-35
Thalidomide
Cat. No.
AKA-35
CAS No.
50-35-1
MF
C13H10N2O4
MW
258.23
Thalidomide binds to the DDB1-CRBN E3 ubiquitin ligase complex.
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Technical Data
Description
Storage and Shipping
References
Product Name
Thalidomide
CAS No.
50-35-1
MF
C13H10N2O4
MW
258.23
Specification
99%
Description
Thalidomide binds to the DDB1-CRBN E3 ubiquitin ligase complex. Packing: 1kg/bag; 25kg/drum or as request Availability: In Stock
Documents
Certificate of Analysis (COA), API specification, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53. PMID: 25043012
[2]. Sun X, et al. Synergistic Inhibition of Thalidomide and Icotinib on Human Non-Small Cell Lung Carcinomas Through ERK and AKT Signaling. Medical Science Monitor. 2018 May 15;24:3193-3203. PMID: 29763936
[3]. Bian C, et al. Thalidomide (THD) alleviates radiation induced lung fibrosis (RILF) via down-regulation of TGF-β/Smad3 signaling pathway in an Nrf2-dependent manner. Free Radical Biology & Medicine. 2018 Dec;129:446-453. PMID: 30339882
[2]. Sun X, et al. Synergistic Inhibition of Thalidomide and Icotinib on Human Non-Small Cell Lung Carcinomas Through ERK and AKT Signaling. Medical Science Monitor. 2018 May 15;24:3193-3203. PMID: 29763936
[3]. Bian C, et al. Thalidomide (THD) alleviates radiation induced lung fibrosis (RILF) via down-regulation of TGF-β/Smad3 signaling pathway in an Nrf2-dependent manner. Free Radical Biology & Medicine. 2018 Dec;129:446-453. PMID: 30339882
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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